| 2021/08/04 | Viljandi Tulevik |  | 10-0 | | Viljandi Tulevik B | ||||
| Paide LM |  | 5-0 |  | Kristiine JK | |||||
| 2021/08/09 | Narva Trans |  | DA |  | Eston Villa | ||||
| 2021/08/16 | Elva |  | 2-0 |  | Viimsi | ||||
| 2021/08/17 | Läänemaa JK |  | 2-8 |  | TJK Legion | ||||
| 2021/08/18 | Nomme Kalju |  | 9-1 |  | Tallinna FC Zapoos | ||||
| JK Tammeka |  | 3-1 |  | Kuressaare | |||||
| 2021/08/23 | Raplamaa |  | 0-5 |  | FCI Levadia | ||||
| 2021/08/25 | FC Ararat |  | 2-3 |  | Tannem Vastseliina | ||||
| 2021/09/01 | Voru FC Helios |  | 0-3 |  | Tartu JK Welco | ||||
| 2021/09/02 | Kalev Tallinn |  | 3-0 |  | Tabasalu JK B | ||||
| 2021/09/21 | Tartu Kalev |  | 4-2 |  | FC Nõmme United | ||||
| FCI Tallinn |  | 2-3 |  | FC Flora B | |||||
| 2021/09/22 | FC Tallinn |  | 1-4 | | Paide LM | ||||
| 2021/10/06 | Parnu JK Poseidon |  | 0-1 | | Tabasalu JK | ||||
| 2021/12/12 | FC Flora C | | 0-14 | | FC Flora |
| Fase | Data | Ora | |||||
|---|---|---|---|---|---|---|---|
| 0 | 1/8 | Tannem Vastseliina | Ann. | Tabasalu JK | 2022-02-05 | 13:00 |
