| 14-05 | 19:30 | Osasuna |  | vs |  | Mallorca | G36 | 2.87 | 3.00 | 3.00 | testa a testa |
| 14-05 | 21:30 | Real Madrid |  | vs |  | Alavés | G36 | 1.23 | 7.35 | 14.90 | testa a testa |
| 14-05 | 22:00 | Girona |  | vs |  | Villarreal | G36 | 1.73 | 4.72 | 4.41 | testa a testa |
| 14-05 | 21:00 | Tottenham |  | vs |  | Manchester City | G34 | 7.50 | 6.02 | 1.40 | testa a testa |
| 15-05 | 00:00 | Racing |  | vs |  | Nacional | GrpF | testa a testa | |||
| 15-05 | 02:00 | Sportivo Ameliano |  | vs |  | Rayo Zuliano FC | GrpE | testa a testa | |||
| 15-05 | 02:00 | Defensa y Justicia |  | vs |  | Independiente Medellín | GrpA | 1.89 | 3.45 | 4.08 | testa a testa |
| 15-05 | 02:30 | Corinthians |  | vs |  | Argentinos Juniors | GrpF | 1.81 | 3.34 | 4.71 | testa a testa |
| 15-05 | 04:00 | Nacional Potosí |  | vs |  | Sportivo Trinidense | GrpD | 1.22 | 6.30 | 11.60 | testa a testa |
| 15-05 | 00:00 | Talleres |  | vs |  | Cobresal | GrpB | 1.19 | 7.00 | 14.50 | testa a testa |
| 15-05 | 00:00 | LDU Quito |  | vs |  | Junior Barranquilla | GrpD | 1.50 | 4.33 | 6.50 | testa a testa |
| 15-05 | 00:00 | Peñarol |  | vs |  | Atlético Mineiro | GrpG | 3.09 | 3.26 | 2.37 | testa a testa |
| 15-05 | 02:30 | River Plate |  | vs |  | Libertad | GrpH | 1.37 | 5.00 | 8.20 | testa a testa |
| 15-05 | 04:00 | Millonarios |  | vs |  | Palestino | GrpE | 1.55 | 4.05 | 6.25 | testa a testa |
| 14-05 | 01:00 | São Paulo |  | 2-1 |  | Fluminense | G6 |
| 14-05 | 00:00 | Gimnasia |  | 3-1 |  | Vélez Sarsfield | 1F | ||||
| 14-05 | 02:00 | Unión |  | 1-0 |  | Banfield | 1F |
