| 2022/10/30 | Los Angeles FC |  | 3-0 |  | Austin FC |
| 2 |
|
Daniel Gazdag Philadelphia Union | 24 G |
| 3 |
|
Hany Mukhtar Nashville SC | 23 G |
| 4 |
|
Brandon Vázquez FC Cincinnati | 19 G |
| 5 |
|
Jesús Ferreira FC Dallas | 18 G |
| 2 |
|
Diego Fagundez Austin FC | 12 AST |
| 2 |
|
Luciano Acosta FC Cincinnati | 12 AST |
| 2 |
|
Carlos Vela Los Angeles FC | 12 AST |
| 5 |
|
Carles Gil NE Revolution | 9 AST |
